Results: Intergroup differences were found in accordance with the cognitive profile of each clinical condition. Intergroup comparisons, ROC curves, and cut-off scores were calculated for the study of diagnostic properties. A comprehensive neuropsychological test battery and CCD were completed. Each clinical group was compared against a healthy control group (HC) with the same number of participants and no significant differences in age, education, and sex. Methods: Sixty participants with AD (50% MCI) and thirty with PD-MCI were enrolled. We aimed to evaluate the diagnostic properties of the CCD in Spaniards for the assessment of patients with Alzheimer’s disease in mild cognitive impairment (AD-MCI) and mild dementia stages (AD-D) and patients with mild cognitive impairment associated with Parkinson’s disease (PD-MCI). Objective: The Cross-Cultural Dementia (CCD) is a new screening tool to evaluate cognitive impairment based on a cross-cultural perspective to reduce the bias of education, and language and cultural differences. 3Department of Psychiatry and Medical Psychology, OLVG Hospital, Amsterdam, Netherlands. 2Faculty of Psychology, Universidad Autónoma de Madrid, Madrid, Spain.1Department of Neurology, Hospital Clinico San Carlos, San Carlos Institute for Health Research (IdiSSC), Universidad Complutense de Madrid, Madrid, Spain.Alfonso Delgado-Álvarez 1,2 Cristina Delgado-Alonso 1 Miriam Goudsmit 3 Rocío García-Ramos 1 María José Gil-Moreno 1 María Valles-Salgado 1 María Díez-Cirarda 1 María Dolores Zamarrón-Cassinello 2 Jorge Matías-Guiu 1 Jordi A.
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